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{"id":2738,"date":"2021-02-08T16:06:31","date_gmt":"2021-02-08T16:06:31","guid":{"rendered":"http:\/\/staging.careersinscience.co\/?p=2738"},"modified":"2021-05-03T11:15:09","modified_gmt":"2021-05-03T10:15:09","slug":"title-3","status":"publish","type":"post","link":"https:\/\/child.imagenscience.com\/archives\/2738","title":{"rendered":"How a retrovirus helped placental mammals"},"content":{"rendered":"\n

The intimate relationship between mother and fetus allows placental mammals to birth live offspring. 
Compared to our egg-laying ancestors, this evolutionary step affords the fetus greater protection within the mother, and has led to a dramatic expansion in brain development.<\/p>\n\n\n\n

But it might surprise you to know that an ancient retrovirus was, in part, responsible for this breakthrough.  <\/p>\n\n\n\n

The syncytiotrophoblast (depicted in the second panel): <\/p>\n\n\n\n

\u2686 A acts as a barrier between the placenta and the maternal tissue.<\/p>\n\n\n\n

\u2686 Contains a protein called syncytin that allows this barrier to form, and which originated from the envelope protein of a retrovirus!<\/p>\n\n\n\n

\u2686 is essential to maintain a close relationship where nutrients and gases can be exchanged, whilst ensuring feto-maternal tolerance and immune suppression.<\/p>\n\n\n\n

\u2686is a multinucleate cell layer of fetal origin.<\/p>\n\n\n\n

Thank you to \ud83c\uddea\ud83c\uddf8 Antonio Garc\u00eda G\u00f3mez. Antonio, holds a PhD in Biochemistry and he is a scientific illustrator passionate about translating scientific messages into effective and engaging illustrations. <\/p>\n\n\n\n