Here, we are going to show you the itinerary of a tissue biopsy:<\/p>\n\n\n\n
1\ufe0f\u20e3 Fixation & Processing.
The sample can\u2019t be used as it is, it has to undergo a number of preparatory steps: fixation to preserve its integrity ( 24-48 hours) and a series of solvents including paraffin wax (12 hours)<\/p>\n\n\n\n
2\ufe0f\u20e3 Sectioning. The sample is now in a hard paraffin wax block and must be cut in sections of 5 micrometres.
Each section will end up in a glass slide (1 hour)<\/p>\n\n\n\n
3\ufe0f\u20e3 Labelling. The glass slide can now be labelled with dyes or antibodies. This will highlight specific features of the sample. (From 1 to 12 hours)<\/p>\n\n\n\n
4\ufe0f\u20e3 Analysis at the #Microscope<\/a>. The pathologist will examine it for indications of disease.<\/p>\n\n\n\n Thank you to \ud83c\uddea\ud83c\uddf8 Cristina Sala Ripoll<\/a>, a freelance scientific illustrator who loves to create infographics and colorful images for science outreach and education.
This illustration was created for the Pathology department at the University Medical Center Groningen, with the collaboration of Dr. Wilfred den Dunnen.<\/p>\n\n\n\n
![\"\"](\"http:\/\/staging.careersinscience.co\/wp-content\/uploads\/2021\/02\/Pathology-lab-resized-1024x631.jpg\")
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