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{"id":2424,"date":"2021-01-27T11:34:52","date_gmt":"2021-01-27T11:34:52","guid":{"rendered":"http:\/\/staging.careersinscience.co\/?p=2424"},"modified":"2021-02-08T22:57:42","modified_gmt":"2021-02-08T22:57:42","slug":"2424-2","status":"publish","type":"post","link":"https:\/\/child.imagenscience.com\/archives\/2424","title":{"rendered":"Unveiling COVID-19’s secrets"},"content":{"rendered":"\n
We have seen the globe-sweeping reality of SARS-CoV-2. <\/p>\n\n\n\n
In order to turn the tide in the pandemic, scientists are searching for the novel coronavirus\u2019s vulnerabilities. <\/p>\n\n\n\n
This infographic illustrates targets in the replication cycle of the virus, and potential therapeutic routes. <\/p>\n\n\n\n
Of particular interest is the virus spike protein, which is:<\/p>\n\n\n\n
\u25cf required for binding and fusion with the host cell membrane \u25cf on the outer surface of the virion \u25cf a target for the immune system and the antigen for all for\u00a0vaccines reporting protection in phase 3 trials\u00a0<\/p>\n\n\n\n
Downstream of entry, targeting replication via either viral proteases or RNA may be possible using anti-virals already in use or in trials. These replication events are common to RNA viruses, rather than specific to SARS-CoV-2.<\/p>\n\n\n\n