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{"id":2424,"date":"2021-01-27T11:34:52","date_gmt":"2021-01-27T11:34:52","guid":{"rendered":"http:\/\/staging.careersinscience.co\/?p=2424"},"modified":"2021-02-08T22:57:42","modified_gmt":"2021-02-08T22:57:42","slug":"2424-2","status":"publish","type":"post","link":"https:\/\/child.imagenscience.com\/archives\/2424","title":{"rendered":"Unveiling COVID-19’s secrets"},"content":{"rendered":"\n

We have seen the globe-sweeping reality of SARS-CoV-2. <\/p>\n\n\n\n

In order to turn the tide in the pandemic, scientists are searching for the novel coronavirus\u2019s vulnerabilities. <\/p>\n\n\n\n

This infographic illustrates targets in the replication cycle of the virus, and potential therapeutic routes. <\/p>\n\n\n\n

Of particular interest is the virus spike protein, which is:<\/p>\n\n\n\n

\u25cf required for binding and fusion with the host cell membrane
\u25cf on the outer surface of the virion
\u25cf a target for the immune system and the antigen for all for\u00a0vaccines reporting protection in phase 3 trials\u00a0<\/p>\n\n\n\n

Downstream of entry, targeting replication via either viral proteases or RNA may be possible using anti-virals already in use or in trials. These replication events are common to RNA viruses, rather than specific to SARS-CoV-2.<\/p>\n\n\n\n

Thank you to noted illustrator and The Johns Hopkins University School of Medicine<\/a> Professor \ud83c\uddfa\ud83c\uddf8 Jennifer E. Fairman, CMI, FAMI<\/a>. Jennifer is also the Founder of Fairman Studios, LLC. The illustration was created for the “COVID-19 Special Edition” of Hopkins Bloomberg Public Health Magazine (magazine: https:\/\/lnkd.in\/ePw-aRC<\/a>; video: youtu.be\/xRTMXvZ75dY<\/a>).<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"

Illustration can help scientists visualize their foe.<\/p>\n","protected":false},"author":2,"featured_media":2725,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"categories":[104],"tags":[105,109,107,106,108],"_links":{"self":[{"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/posts\/2424"}],"collection":[{"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/comments?post=2424"}],"version-history":[{"count":6,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/posts\/2424\/revisions"}],"predecessor-version":[{"id":2791,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/posts\/2424\/revisions\/2791"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/media\/2725"}],"wp:attachment":[{"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/media?parent=2424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/categories?post=2424"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/child.imagenscience.com\/wp-json\/wp\/v2\/tags?post=2424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}